HDAC7 Protein (AA 1-164, partial) (His tag)
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- Antigène Voir toutes HDAC7 Protéines
- HDAC7 (Histone Deacetylase 7 (HDAC7))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-164, partial
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette HDAC7 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- PGADGTQVSP GAHYCSPTGA GCPRPCADTP GPQPQPMDLR VGQRPPVEPP PEPTLLALQR PQRLHHHLFL AGLQQQRSVE PMRLSMDTPM PELQVGPQEQ ELRQLLHKDK SKRSAVASSV VKQKLAEVIL KKQQAALERT VHPNSPGIPY RTLEPLETEG ATRSMLSSFL PPVPSLPSDP PEHFPLRKTV SEPNLKLRYK
- Purification
- SDS-PAGE
- Pureté
- > 90 %
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Histone Deacetylase 7 (HDAC7) (AA 1-276) protein (GST tag)
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Histone Deacetylase 7 (HDAC7) (AA 1-952) protein (Strep Tag)Crystallography grade HDAC7 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Histone Deacetylase 7 (HDAC7) (AA 1-938) protein (Strep Tag)Crystallography grade HDAC7 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Histone Deacetylase 7 (HDAC7) (AA 645-915), (partial) protein (His tag)HDAC7 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
Histone Deacetylase 7 (HDAC7) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HDAC7 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Histone Deacetylase 7 (HDAC7) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HDAC7 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- HDAC7 (Histone Deacetylase 7 (HDAC7))
- Autre désignation
- HDAC7 (HDAC7 Produits)
- Synonymes
- HD7A Protein, HDAC7A Protein, 5830434K02Rik Protein, HD7 Protein, HD7a Protein, Hdac7a Protein, mFLJ00062 Protein, hdac7a Protein, K2K18.5 Protein, K2K18_5 Protein, histone deacetylase7 Protein, histone deacetylase 7 Protein, histone deacetylase7 Protein, HDAC7 Protein, Hdac7 Protein, hdac7 Protein, HDA7 Protein
- Sujet
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors . May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 .
- Poids moléculaire
- 26.1 kDa
- UniProt
- Q8WUI4
- Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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