TNFL6 Protein (AA 130-281, Cytoplasmic Domain, Cytosolic) (His tag)

N° du produit ABIN5713444

Détail du produit

Antigène: TNFL6 (Tumor Necrosis Factor Ligand Superfamily Member 6 (TNFL6))

Type de proteíne: Recombinant

Attributs du protein: AA 130-281, Cytosolic, Cytoplasmic Domain

Origine: Humain

Source: Levure

Purification/Conjugué: Cette TNFL6 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: QIGHPSPPPE KKELRKVAHL TGKSNSRSMP LEWEDTYGIV LLSGVKYKKG GLVINETGLY FVYSKVYFRG QSCNNLPLSH KVYMRNSKYP QDLVMMEGKM MSYCTTGQMW ARSSYLGAVF NLTSADHLYV NVSELSLVNF EESQTFFGLY KL

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: TNFL6 (Tumor Necrosis Factor Ligand Superfamily Member 6 (TNFL6))

Autre désignation: TNFL6 (TNFL6 Produits)

Sujet: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Poids moléculaire: 19.3 kDa

UniProt: P48023