MAGEA1 Protein (AA 1-309, full length) (His tag)

N° du produit ABIN5713624

Détail du produit

Antigène: MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))

Type de proteíne: Recombinant

Attributs du protein: full length, AA 1-309

Origine: Humain

Source: Levure

Purification/Conjugué: Cette MAGEA1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MSLEQRSLHC KPEEALEAQQ EALGLVCVQA AASSSSPLVL GTLEEVPTAG STDPPQSPQG ASAFPTTINF TRQRQPSEGS SSREEEGPST SCILESLFRA VITKKVADLV GFLLLKYRAR EPVTKAEMLE SVIKNYKHCF PEIFGKASES LQLVFGIDVK EADPTGHSYV LVTCLGLSYD GLLGDNQIMP KTGFLIIVLV MIAMEGGHAP EEEIWEELSV MEVYDGREHS AYGEPRKLLT QDLVQEKYLE YRQVPDSDPA RYEFLWGPRA LAETSYVKVL EYVIKVSARV RFFFPSLREA ALREEEEGV

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: MAGEA1 (Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) (MAGEA1))

Autre désignation: MAGA1 (MAGEA1 Produits)

Synonymes: CT1.1 Protein, MAGE1 Protein, Mage-a1 Protein, MAGE family member A1 Protein, melanoma antigen, family A, 1 Protein, MAGEA1 Protein, Magea1 Protein

Sujet: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in bryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Poids moléculaire: 36.31 kDa

UniProt: P43355