NADPH Oxidase 4 Protein (NOX4) (AA 210-424, Extracellular) (His-SUMO Tag)

N° du produit ABIN5713704

Détail du produit

Antigène: NADPH Oxidase 4 (NOX4)

Type de proteíne: Recombinant

Attributs du protein: Extracellular, AA 210-424

Origine: Rat

Source: Levure

Purification/Conjugué: Cette NADPH Oxidase 4 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: GGLLKYQTNL DTHPPGCISL NRTPSQNMSI ADYVSEHFHG SLPGGFSKLE DHYQKTLVKI CLEEPKFQAH FPQTWIWISG PLCLYCAERL YRCIRSNKPV TIISVINHPS DVMELRMIKE NFKARPGQYI ILHCPSVSAL ENHPFTLTMC PTETKATFGV HFKVVGDWTE RFRDLLLPPS SQDSEILPFI QSRNYPKLYI DGPFGSPFEE SLNYE

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: NADPH Oxidase 4 (NOX4)

Autre désignation: NOX4 (NOX4 Produits)

Synonymes: KOX Protein, KOX-1 Protein, RENOX Protein, AI648021 Protein, nox4 Protein, NOX4 Protein, NADPH oxidase 4 Protein, NOX4 Protein, Nox4 Protein, nox4 Protein, PTRG_09562 Protein

Sujet: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.

Poids moléculaire: 40.6 kDa

UniProt: Q924V1

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration