TNFAIP8 Protein (AA 1-198) (His tag)

N° du produit ABIN5853025

Détail du produit

Antigène: TNFAIP8 (Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8))

Type de proteíne: Recombinant

Attributs du protein: AA 1-198

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TNFAIP8 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMHSEAEE SKEVATDVFN SKNLAVQAQK KILGKMVSKS IATTLIDDTS SEVLDELYRV TREYTQNKKE AEKIIKNLIK TVIKLAILYR NNQFNQDELA LMEKFKKKVH QLAMTVVSFH QVDYTFDRNV LSRLLNECRE MLHQIIQRHL TAKSHGRVNN VFDHFSDCEF LAALYNPFGN FKPHLQKLCD GINKMLDEEN I

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: TNFAIP8 (Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8))

Autre désignation: TNFAIP8 (TNFAIP8 Produits)

Synonymes: MGC55331 Protein, zgc:55331 Protein, si:dkey-49m19.6 Protein, GG2-1 Protein, MDC-3.13 Protein, SCC-S2 Protein, SCCS2 Protein, AA987150 Protein, E130304C20Rik Protein, ENSMUSG00000073567 Protein, Gg2-1 Protein, Gm10539 Protein, Nded Protein, Ssc-2 Protein, tumor necrosis factor, alpha-induced protein 8-like 1 Protein, TNF alpha induced protein 8 S homeolog Protein, TNF alpha induced protein 8 Protein, tumor necrosis factor, alpha-induced protein 8 Protein, tnfaip8l1 Protein, tnfaip8.S Protein, TNFAIP8 Protein, Tnfaip8 Protein

Sujet: TNFAIP8 belongs to the TNFAIP8 family. This protein acts as a negative mediator of apoptosis and may play a role in tumor progression. It suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Recombinant human TNFAIP8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 25kDa (221aa), confirmed by MALDI-TOF

NCBI Accession: NP_055165

UniProt: O95379