CNOT8 Protein (AA 1-292) (His tag)

N° du produit ABIN5853036

Détail du produit

Antigène: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Type de proteíne: Recombinant

Attributs du protein: AA 1-292

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CNOT8 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMPAALVE NSQVICEVWA SNLEEEMRKI REIVLSYSYI AMDTEFPGVV VRPIGEFRSS IDYQYQLLRC NVDLLKIIQL GLTFTNEKGE YPSGINTWQF NFKFNLTEDM YSQDSIDLLA NSGLQFQKHE EEGIDTLHFA ELLMTSGVVL CDNVKWLSFH SGYDFGYMVK LLTDSRLPEE EHEFFHILNL FFPSIYDVKY LMKSCKNLKG GLQEVADQLD LQRIGRQHQA GSDSLLTGMA FFRMKELFFE DSIDDAKYCG RLYGLGTGVA QKQNEDVDSA QEKMSILAII NNMQQ

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Autre désignation: CNOT8 (CNOT8 Produits)

Synonymes: calif Protein, pop2 Protein, zgc:63844 Protein, wu:fe49a05 Protein, caf1 Protein, hcaf1 Protein, CAF1 Protein, CALIF Protein, Caf1b Protein, POP2 Protein, hCAF1 Protein, 1500015I04Rik Protein, 1810022F04Rik Protein, AA536816 Protein, AU015770 Protein, AU043059 Protein, CCR4-NOT transcription complex, subunit 8 Protein, CCR4-NOT transcription complex subunit 8 Protein, CCR4-NOT transcription complex subunit 8 S homeolog Protein, Cnot8 Protein, CNOT8 Protein, cnot8.S Protein, cnot8 Protein, PAAG_04884 Protein, VDBG_08730 Protein

Sujet: CNOT8 belongs to the CAF1 family. It is a ubiquitous transcription factor required for a diverse set of processes and functions as part of the CCR-NOT complex. The CCR4-NOT complex functions as general transcription regulation complex. This complex contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8 and binds BTG2. Recombinant human CNOT8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 35.9 kDa (315aa), confirmed by MALDI-TOF

NCBI Accession: NP_004770

UniProt: Q9UFF9