KLF7 Protein (AA 1-302) (His tag)

N° du produit ABIN5853049

Détail du produit

Antigène: KLF7 (Kruppel-Like Factor 7 (Ubiquitous) (KLF7))

Type de proteíne: Recombinant

Attributs du protein: AA 1-302

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette KLF7 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMDVLASY SIFQELQLVH DTGYFSALPS LEETWQQTCL ELERYLQTEP RRISETFGED LDCFLHASPP PCIEESFRRL DPLLLPVEAA ICEKSSAVDI LLSRDKLLSE TCLSLQPASS SLDSYTAVNQ AQLNAVTSLT PPSSPELSRH LVKTSQTLSA VDGTVTLKLV AKKAALSSVK VGGVATAAAA VTAAGAVKSG QSDSDQGGLG AEACPENKKR VHRCQFNGCR KVYTKSSHLK AHQRTHTGEK PYKCSWEGCE WRFARSDELT RHYRKHTGAK PFKCNHCDRC FSRSDHLALH MKRHI

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: KLF7 (Kruppel-Like Factor 7 (Ubiquitous) (KLF7))

Autre désignation: KLF7 (KLF7 Produits)

Synonymes: klf7 Protein, MGC64357 Protein, KLF7 Protein, zgc:112027 Protein, uklf Protein, MGC146361 Protein, UKLF Protein, 9830124P08Rik Protein, Kruppel-like factor 7 (ubiquitous) S homeolog Protein, Kruppel like factor 7 Protein, Kruppel-like factor 7a Protein, Kruppel-like factor 7 (ubiquitous) Protein, klf7.S Protein, KLF7 Protein, klf7a Protein, klf7 Protein, Klf7 Protein

Sujet: KLF7 is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. Recombinant human KLF7 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 35.8kDa (325aa)

NCBI Accession: NP_003700

UniProt: O75840