HLA-DOA Protein (AA 26-217) (His tag)

N° du produit ABIN5853061

Détail du produit

Antigène: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Type de proteíne: Recombinant

Attributs du protein: AA 26-217

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HLA-DOA protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSTKADHMG SYGPAFYQSY GASGQFTHEF DEEQLFSVDL KKSEAVWRLP EFGDFARFDP QGGLAGIAAI KAHLDILVER SNRSRAINVP PRVTVLPKSR VELGQPNILI CIVDNIFPPV INITWLRNGQ TVTEGVAQTS FYSQPDHLFR KFHYLPFVPS AEDVYDCQVE HWGLDAPLLR HWELQVPIPP PDAME

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Autre désignation: HLA-DOA (HLA-DOA Produits)

Synonymes: HLA-DNA Protein, HLA-DZA Protein, HLADZ Protein, major histocompatibility complex, class II, DO alpha Protein, HLA-DOA Protein

Sujet: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. Recombinant human HLA-DAO protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 24.1 kDa (215aa)

NCBI Accession: NP_002110

UniProt: P06340