FHL3 Protein (AA 1-280) (His tag)

N° du produit ABIN5853348

Détail du produit

Antigène: FHL3 (Four and A Half LIM Domains 3 (FHL3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-280

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FHL3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMSESFDC AKCNESLYGR KYIQTDSGPY CVPCYDNTFA NTCAECQQLI GHDSRELFYE DRHFHEGCFR CCRCQRSLAD EPFTCQDSEL LCNDCYCSAF SSQCSACGET VMPGSRKLEY GGQTWHEHCF LCSGCEQPLG SRSFVPDKGA HYCVPCYENK FAPRCARCSK TLTQGGVTYR DQPWHRECLV CTGCQTPLAG QQFTSRDEDP YCVACFGELF APKCSSCKRP IVGLGGGKYV SFEDRHWHHN CFSCARCSTS LVGQGFVPDG DQVLCQGCSQ AGP

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: FHL3 (Four and A Half LIM Domains 3 (FHL3))

Autre désignation: FHL3 (FHL3 Produits)

Synonymes: slim2 Protein, MGC79794 Protein, fb09g09 Protein, wu:fb09g09 Protein, zgc:63514 Protein, fd57e01 Protein, fhl3 Protein, wu:fd57e01 Protein, SLIM2 Protein, four and a half LIM domains 3 Protein, four and a half LIM domains 3 S homeolog Protein, four and a half LIM domains 3b Protein, four and a half LIM domains 3a Protein, FHL3 Protein, fhl3.S Protein, fhl3 Protein, fhl3b Protein, fhl3a Protein, Fhl3 Protein

Sujet: FHL3 is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human FHL3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 33.6 kDa (303aa) confirmed by MALDI-TOF

NCBI Accession: NP_004459

UniProt: Q13643