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SHFM1 Protein (AA 1-70) (His tag)
SHFM1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 85 % by SDS - PAGE
SDS
N° du produit ABIN5853387
Détail du produit
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Antigène
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SHFM1
(Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1))
Type de proteíne
Recombinant
Attributs du protein
AA 1-70
Origine
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Humain
Source
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Escherichia coli (E. coli)
Purification/Conjugué
Cette SHFM1 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
MGSSHHHHHH SSGLVPRGSH MGSMSEKKQP VDLGLLEEDD EFEEFPAEDW AGLDEDEDAH VWEDNWDDDN VEDDFSNQLR AELEKHGYKM ETS
Pureté
> 85 % by SDS - PAGE
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.1M NaCl
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
SHFM1
(Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1))
Autre désignation
SHFM1 (SHFM1 Produits )
Synonymes
DSS1 Protein, ECD Protein, SEM1 Protein, SHFD1 Protein, SHSF1 Protein, Shfdg1 Protein, Shfg Protein, Dss1 Protein, SHFM1 Protein, dss1 Protein, ecd Protein, sem1 Protein, shfd1 Protein, shfdg1 Protein, shfm1 Protein, shfm1.S Protein, shsf1 Protein, wu:fb55c02 Protein, zgc:56203 Protein, zgc:85901 Protein, SEM1, 26S proteasome complex subunit Protein, SEM1, 26S proteasome complex subunit S homeolog Protein, SEM1 Protein, Sem1 Protein, sem1.S Protein, sem1 Protein
Sujet
SHFM1, as known as 26S proteasome complex subunit DSS1, has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. Recombinant human SHFM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Poids moléculaire
10.7kDa (93aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
NCBI Accession
NP_006295
UniProt
P60896
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