MGAT2 Protein (AA 30-447) (His tag)

N° du produit ABIN5853617

Détail du produit

Antigène: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Type de proteíne: Recombinant

Attributs du protein: AA 30-447

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MGAT2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MRQRKNEALA PPLLDAEPAR GAGGRGGDHP SVAVGIRRVS NVSAASLVPA VPQPEADNLT LRYRSLVYQL NFDQTLRNVD KAGTWAPREL VLVVQVHNRP EYLRLLLDSL RKAQGIDNVL VIFSHDFWST EINQLIAGVN FCPVLQVFFP FSIQLYPNEF PGSDPRDCPR DLPKNAALKL GCINAEYPDS FGHYREAKFS QTKHHWWWKL HFVWERVKIL RDYAGLILFL EEDHYLAPDF YHVFKKMWKL KQQECPECDV LSLGTYSASR SFYGMADKVD VKTWKSTEHN MGLALTRNAY QKLIECTDTF CTYDDYNWDW TLQYLTVSCL PKFWKVLVPQ IPRIFHAGDC GMHHKKTCRP STQSAQIESL LNNNKQYMFP ETLTISEKFT VVAISPPRKN GGWGDIRDHE LCKSYRRLQ

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Autre désignation: MGAT2 (MGAT2 Produits)

Synonymes: CDG2A Protein, CDGS2 Protein, GLCNACTII Protein, GNT-II Protein, GNT2 Protein, CG7921 Protein, Dmel\\CG7921 Protein, GlcNAc-TII Protein, GlcNAcT2 Protein, dMGAT2 Protein, MGC89475 Protein, Gnt2 Protein, AA407964 Protein, CH73-301C19.1 Protein, zgc:162268 Protein, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase Protein, CG7921 gene product from transcript CG7921-RB Protein, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog Protein, mannoside acetylglucosaminyltransferase 2 Protein, MGAT2 Protein, Mgat2 Protein, mgat2.L Protein, mgat2 Protein

Sujet: MGAT2 is a golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. Transcript variants with a spliced 5' uTR may exist, but their biological validity has not been determined. Recombinant human MGAT2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 50 kDa (439aa)

NCBI Accession: NP_002399

UniProt: Q10469