PURB Protein (AA 1-312) (His tag)

N° du produit ABIN5853711

Détail du produit

Antigène: PURB (Purine-Rich Element Binding Protein B (PURB))

Type de proteíne: Recombinant

Attributs du protein: AA 1-312

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PURB protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMADGDSG SERGGGGGPC GFQPASRGGG EQETQELASK RLDIQNKRFY LDVKQNAKGR FLKIAEVGAG GSKSRLTLSM AVAAEFRDSL GDFIEHYAQL GPSSPEQLAA GAEEGGGPRR ALKSEFLVRE NRKYYLDLKE NQRGRFLRIR QTVNRGGGGF GAGPGPGGLQ SGQTIALPAQ GLIEFRDALA KLIDDYGGED DELAGGPGGG AGGPGGGLYG ELPEGTSITV DSKRFFFDVG CNKYGVFLRV SEVKPSYRNA ITVPFKAWGK FGGAFCRYAD EMKEIQERQR DKLYERRGGG SGGGEESEGE EVDED

Pureté: > 95 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: PURB (Purine-Rich Element Binding Protein B (PURB))

Autre désignation: PuRB (PURB Produits)

Synonymes: 2310015K15Rik Protein, AA114818 Protein, Cager-2 Protein, D11Bwg0414e Protein, pur-beta Protein, purb Protein, zgc:65916 Protein, purb-b Protein, purbeta Protein, PURBETA Protein, si:dkey-202n14.1 Protein, purine rich element binding protein B Protein, purine-rich element binding protein Bb Protein, purine-rich element binding protein B L homeolog Protein, purine-rich element binding protein Ba Protein, Purb Protein, purbb Protein, purb.L Protein, PURB Protein, purba Protein

Sujet: PuRB is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PuR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. Recombinant human PuRB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 35.6kDa (335aa) confirmed by MALDI-TOF

NCBI Accession: NP_150093

UniProt: Q96QR8