LMX1B Protein (AA 1-395) (His tag)

N° du produit ABIN5853769

Détail du produit

Antigène: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Type de proteíne: Recombinant

Attributs du protein: AA 1-395

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LMX1B protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMDIATGP ESLERCFPRG QTDCAKMLDG IKMEEHALRP GPATLGVLLG SDCPHPAVCE GCQRPISDRF LMRVNESSWH EECLQCAACQ QALTTSCYFR DRKLYCKQDY QQLFAAKCSG CMEKIAPTEF VMRALECVYH LGCFCCCVCE RQLRKGDEFV LKEGQLLCKG DYEKEKDLLS SVSPDESDSV KSEDEDGDMK PAKGQGSQSK GSGDDGKDPR RPKRPRTILT TQQRRAFKAS FEVSSKPCRK VRETLAAETG LSVRVVQVWF QNQRAKMKKL ARRHQQQQEQ QNSQRLGQEV LSSRMEGMMA SYTPLAPPQQ QIVAMEQSPY GSSDPFQQGL TPPQMPGNDS IFHDIDSDTS LTSLSDCFLG SSDVGSLQAR VGNPIDRLYS MQSSYFAS

Pureté: > 80 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: iquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Autre désignation: LMX1B (LMX1B Produits)

Synonymes: LMX1.2 Protein, NPS1 Protein, LMX Protein, LMX1 Protein, LMX1.1 Protein, lmx1b Protein, lmx1b.1 Protein, Xlmx1b Protein, lmx1b.2 Protein, LIM homeobox transcription factor 1 beta Protein, LIM homeobox transcription factor 1, beta b Protein, LIM homeobox transcription factor 1, beta, gene 1 S homeolog Protein, LIM homeobox transcription factor 1, beta a Protein, LMX1B Protein, Lmx1b Protein, lmx1bb Protein, lmx1b.1.S Protein, lmx1ba Protein

Sujet: LMX1B is a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human LMX1B protein, fused to His-tag at N-terminus, was expressed in E.coli .

Poids moléculaire: 46.5 kDa (418 aa)

NCBI Accession: NP_002307

UniProt: O60663

Pathways: Dopaminergic Neurogenesis