GCHFR Protein (AA 1-84) (His tag)

N° du produit ABIN5853779

Détail du produit

Antigène: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Type de proteíne: Recombinant

Attributs du protein: AA 1-84

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GCHFR protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMPYLLIS TQIRMEVGPT MVGDEQSDPE LMQHLGASKR RALGNNFYEY YVDDPPRIVL DKLERRGFRV LSMTGVGQTL VWCLHKE

Pureté: > 95 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 40 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Autre désignation: GCHFR (GCHFR Produits)

Synonymes: GFRP Protein, HsT16933 Protein, P35 Protein, 2010323F13Rik Protein, GTP cyclohydrolase I feedback regulator Protein, GCHFR Protein, Gchfr Protein

Sujet: GTP cyclohydrolase I feedback regulatory protein(GCHFR) binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. Recombinant human GCHFR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 12.1 kDa (107aa) confirmed by MALDI-TOF

NCBI Accession: NP_005249

UniProt: P30047