HCV Core Protein Protein (AA 1-120) (His tag)

N° du produit ABIN5853816

Détail du produit

Antigène: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Type de proteíne: Recombinant

Attributs du protein: AA 1-120

Origine: Hepatitis C Virus (HCV)

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HCV Core Protein protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MSTNPKPQRK TKRNTNRRPQ DVKFPGGGQI VGGVYLLPRR GPRLGVRATR KTSERSQPRG RRQPIPKARR PEGRTWAQPG YPWPLYGNEG CGWAGWLLSP RGSRPSWGPT DPRRRSRNLG

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Autre désignation: HCV-Core (HCV C Produits)

Classe de substances: Viral Protein

Sujet: HCV-Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. It modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit and also regulates many host cellular functions such as signaling pathways and apoptosis. HCV-Core prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Recombinant Hepatitis C virus Core protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 15.7 kDa (140aa)