FDFT1 Protein (AA 1-283) (His tag)
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- Antigène Voir toutes FDFT1 Protéines
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-283
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette FDFT1 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MGSMEFVKCL GHPEEFYNLV RFRIGGKRKV MPKMDQDSLS SSLKTCYKYL NQTSRSFAAV IQALDGEMRN AVCIFYLVLR ALDTLEDDMT ISVEKKVPLL HNFHSFLYQP DWRFMESKEK DRQVLEDFPT ISLEFRNLAE KYQTVIADIC RRMGIGMAEF LDKHVTSEQE WDKYCHYVAG LVGIGLSRLF SASEFEDPLV GEDTERANSM GLFLQKTNII RDYLEDQQGG REFWPQEVWS RYVKKLGDFA KPENIDLAVQ CLNELITNAL HHIPDVITYL SRLRNQ
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product FDFT1 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
- Autre désignation
- FDFT1 (FDFT1 Produits)
- Synonymes
- FDFT1 Protein, DKFZp459C1712 Protein, SQS Protein, SS Protein, DGPT Protein, ERG9 Protein, fdft1 Protein, farnesyl-diphosphate farnesyltransferase 1 Protein, squalene synthase Protein, farnesyl diphosphate farnesyl transferase 1 Protein, FDFT1 Protein, fdft1 Protein, LOC100560926 Protein, Fdft1 Protein
- Sujet
- FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Recombinant human FDFT1 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Poids moléculaire
- 35.4 kDa ( 306aa)
- NCBI Accession
- NP_004453
- UniProt
- P37268
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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