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THOC7 Protein (AA 1-204) (His tag)

THOC7 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN5854049
  • Antigène Voir toutes THOC7 Protéines
    THOC7 (THO Complex 7 (THOC7))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-204
    Origine
    • 4
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette THOC7 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MGSSHHHHHH SSGLVPRGSH MGSMGAVTDD EVIRKRLLID GDGAGDDRRI NLLVKSFIKW CNSGSQEEGY SQYQRMLSTL SQCEFSMGKT LLVYDMNLRE MENYEKIYKE IECSIAGAHE KIAECKKQIL QAKRIRKNRQ EYDALAKVIQ HHPDRHETLK ELEALGKELE HLSHIKESVE DKLELRRKQF HVLLSTIHEL QQTLENDEKL SEVEEAQEAS METDPKP
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product THOC7 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate buffered saline (  pH 7.4) containing, 50 % glycerol, 1  mM DTT
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    THOC7 (THO Complex 7 (THOC7))
    Autre désignation
    THOC7 (THOC7 Produits)
    Synonymes
    RGD1305475 Protein, NIF3L1BP1 Protein, fSAP24 Protein, 1500006O09Rik Protein, 9230101K24Rik Protein, Nif3l1bp1 Protein, THO complex 7 Protein, Thoc7 Protein, THOC7 Protein
    Sujet
    THOC7 is required for efficient export of polyadenylated RNA. This protein acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Recombinant human THOC7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Poids moléculaire
    26.1kDa (227aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_079351
    UniProt
    Q6I9Y2
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