UCHL3 Protein (AA 1-230) (His tag)

N° du produit ABIN5854666

Détail du produit

Antigène: UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-230

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette UCHL3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ICPLQCICTE RHRHVDCSGR NLSTLPSGLQ ENIIHLNLSY NHFTDLHNQL TQYTNLRTLD ISNNRLESLP AHLPRSLWNM SAANNNIKLL DKSDTAYQWN LKYLDVSKNM LEKVVLIKNT LRSLEVLNLS SNKLWTVPTN MPSKLHIVDL SNNSLTQILP GTLINLTNLT HLYLHNNKFT FIPDQSFDQL FQLQEITLYN NRWSCDHKQN ITYLLKWMME TKAHVIGTPC STQISSLKEH NMYPTPSGFT SSLFTVSGMQ TVDTINSLSV VTQPKVTKIP KQYRTKETTF GATLSKDTTF TSTDKAFVPY PEDTSTETIN SHEAAAATLT IHLQDGMVTN TSLTSSTKSS PTPMTLSITS GMPNNFSEMP QQSTTLNLWR EETTTNVKTP LPSVEHHHHH H

Pureté: > 95 % by SDS - PAGE.

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Bioactivity Validated

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))

Autre désignation: Uchl3 (Uchl3 Produits)

Synonymes: UCH-L3 Protein, UCH-6 Protein, RGD1561196 Protein, im:6908825 Protein, zgc:109963 Protein, uchl4 Protein, ubiquitin C-terminal hydrolase L3 Protein, ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) Protein, ubiquitin C-terminal hydrolase L3 L homeolog Protein, UCHL3 Protein, Uchl3 Protein, uchl3 Protein, uchl3.L Protein

Sujet: OMG, also known as oligodendrocyte-myelin glycoprotein, is a cell membrane protein which contains eight leucine-rich repeats. This protein is expressed on the surface of oligodendrocytes and on large projection neurons, including Purkinje cells of the cerebellum, pyramidal cells of the hippocampus, motoneurons of the brainstem and anterior horn cells of the spinal cord. The neurite outgrowth inhibitory activities of all three myelin-derived proteins are mediated by binding to a common receptor complex consisting of the Nogo receptor and te p75 neurotrophin receptor. Recombinant human OMG, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 45.4kDa (401aa) 50-100KDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_002535

UniProt: P23515

Pathways: Feeding Behaviour, Positive Regulation of fat Cell Differentiation