CD158F Protein, KIR2DL5 Protein, KIR2DL5.1 Protein, KIR2DL5.3 Protein, KIR2DL5B Protein, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A Protein, KIR2DL5A Protein
Sujet
KIR2DL5A, also known as killer cell immunoglobulin-like receptor 2DL5A, is a type I transmembrane glycoprotein that belongs to the killer cell Ig-like receptor (KIR) family. It is detected on the cell surface as a monomer that, upon tyrosine phosphorylation, recruits the Src homology region 2-containing protein tyrosine phosphatase-2, It is thus an inhibitory receptor gathering a combination of genetic, structural, and functional features unique among KIR, which suggests that it plays a specialized role in innate immunity. Recombinant human KIR2DL5A, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
50.5kDa (459aa) 50-70kDa (SDS-PAGE under reducing conditions)