CD79a Protein (AA 33-143) (His tag)

N° du produit ABIN5854979

Détail du produit

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Type de proteíne: Recombinant

Attributs du protein: AA 33-143

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette CD79a protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: LWMHKVPASL MVSLGEDAHF QCPHNSSNNA NVTWWRVLHG NYTWPPEFLG PGEDPNGTLI IQNVNKSHGG IYVCRVQEGN ESYQQSCGTY LRVRQPPPRP FLDMGEGTKN RLEHHHHHH

Pureté: > 95 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Autre désignation: CD79A (CD79A Produits)

Synonymes: CD79A Protein, Ig-alpha Protein, Iga Protein, Igalpha Protein, Ly-54 Protein, Ly54 Protein, mb-1 Protein, IGA Protein, MB-1 Protein, IG-alpha Protein, CD79a molecule Protein, CD79A antigen (immunoglobulin-associated alpha) Protein, Cd79a molecule-like Protein, CD79A Protein, Cd79a Protein, Cd79al Protein

Sujet: CD79A, also known as B-cell antigen receptor complex-associated protein alpha chain isoform 1, is a membrane-spanning, signal-transducing components of the B-cell receptor. It plays multiple and diverse roles in B cell development and function. It can be a cause of agammaglobulinemia. It is upregulated on MDSCs and activated in response to soluble factors secreted by tumor cells. It plays a functional role in the tumor promoting effects of myeloid cells, and may represent a novel target for cancer therapy. Recombinant human CD79A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 13.6kDa (119aa) 18-28kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_001774

UniProt: P11912

Pathways: BCR Signaling