SH2D1B Protein (AA 1-132) (His tag)

N° du produit ABIN5854982

Détail du produit

Antigène: SH2D1B (SH2 Domain Containing 1B (SH2D1B))

Type de proteíne: Recombinant

Attributs du protein: AA 1-132

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette SH2D1B protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPMDLPYYH GRLTKQDCET LLLKEGVDGN FLLRDSESIP GVLCLCVSFK NIVYTYRIFR EKHGYYRIQT AEGSPKQVFP SLKELISKFE KPNQGMVVHL LKPIKRTSPS LRWRGLKLEL ETFVNSNSDY VDVLPHHHHH H

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 20 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: SH2D1B (SH2 Domain Containing 1B (SH2D1B))

Autre désignation: SH2D1B (SH2D1B Produits)

Synonymes: EAT2 Protein, Sh2d1b1 Protein, RGD1563935 Protein, SH2 domain containing 1B Protein, SH2D1B Protein, Sh2d1b Protein

Sujet: SH2D1B, also known as SH2 domain-containing protein 1B, is one of the proteins which activate NK cells. It plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. Two isoforms of the human protein are produced by alternative splicing. Recombinant human SH2D1B protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 16.4kDa (141aa) 18-28KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_444512

UniProt: O14796

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process