HCST Protein (AA 20-48) (hIgG-His-tag)

N° du produit ABIN7281338

Détail du produit

Antigène: HCST (Hematopoietic Cell Signal Transducer (HCST))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 20-48

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HCST protéine est marqué à la hIgG-His-tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MHRHHPREMK KRVEDLHVGA TVAPSSRRDF TFDLYRALAS AAPSQNIFFS PVSISMSLAM LSLGAGSSTK MQILEGLGLN LQKSSEKELH RGFQQLLQEL NQPRDGFQLS LGNALFTDLV VDLQDTFVSA MKTLYLADTF PTNFRDSAGA MKQINDYVAK QTKGKIVDLL KNLDSNAVVI MVNYIFFKAK WETSFNHKGT QEQDFYVTSE TVVRVPMMSR EDQYHYLLDR NLSCRVVGVP YQGNATALFI LPSEGKMQQV ENGLSEKTLR KWLKMFKKRQ LELYLPKFSI EGSYQLEKVL PSLGISNVFT SHADLSGISN HSNIQVSEMV HKAVVEVDES GTRAAAATGT IFTFRSARLN SQRLVFNRPF LMFIVDNNIL FLGKVNRP

Pureté: > 90 % by SDS - PAGE

Biological Activity Comment: Measured by its ability to inhibit Thrombin cleavage of substrate Boc-VPR-AMC. The IC50 for this effect is less or equal to 2 nM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20 mM MES buffer (  pH 6.0) containing 150  mM NaCl, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: HCST (Hematopoietic Cell Signal Transducer (HCST))

Autre désignation: HCST (HCST Produits)

Synonymes: DAP10 Protein, KAP10 Protein, PIK3AP Protein, Dap10 Protein, HCST Protein, dap10 Protein, dap10-A Protein, hcst Protein, hcsta Protein, kap10 Protein, pik3ap Protein, hematopoietic cell signal transducer Protein, hematopoietic cell signal transducer L homeolog Protein, HCST Protein, Hcst Protein, hcst Protein, hcst.L Protein

Sujet: Serpin A5, also known as PCI (Protein C Inhibitor) or PAI3 (plasminogen activator inhibitor 3), is a member of the serpin serine proteinase inhibitor family. This protein inhibits plasminogen activators as well as activated protein C. Serpin A5 is secreted in plasma, but is also expressed in liver. Serpin A5 is involved in cell inflammation, proliferation, apoptosis, tumor cell migration, invasion, and metastasis. Recombinant Serpin A5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 45.9 kDa (408aa), confirmed by MALDI-TOF

UniProt: P05154