FGF2 Protéine

N° du produit ABIN623547

Cette protéine Recombinant FGF2 est exprimée dans not_set.

Aperçu rapide pour FGF2 Protéine (ABIN623547)

Antigène: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Type de proteíne: Recombinant

Origine: Boeuf (Vache)

Hôte: Veuillez nous consulter SVP

Pureté: > 97.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Détail du produit

Séquence: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Ala-Gly-Ser.

Attributs du produit: Recombinant Bovine Fibroblast Growth Factor-basic

Stérilité: Sterile

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm using the absorbency value of 0.85 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program

Buffer: The FGF-b Bovine was lyophilized from a concentrated (1mg/ml) sterile solution containing 1%HSA.It is recommended to reconstitute the lyophilized Fibroblast Growth Factor-2 Bovine Recombinant in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stock: -20 °C

Détail du antigène

Antigène: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Autre désignation: Fibroblast Growth Factor-Basic

Sujet: FGF-2 Bovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 155 amino acids and having a molecular mass of 17250 Dalton. The Fibroblast Growth Factor 2 is purified by proprietary chromatographic techniques. Introduction: FGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. there are differences in the tissue distribution and concentration of these 2 growth factors. Synonyms: HBGH-2, HBGF-2, Prostatropin, FGF-2, FGB-b.

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins