BMP7 Protein (AA 292-430) (His tag)
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- Antigène Voir toutes BMP7 Protéines
- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
- Activité biologique
- Active
- Attributs du protein
- AA 292-430
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Origine
- Souris
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette BMP7 protéine est marqué à la His tag.
- Application
- Activity Assay (AcA), Cell Culture (CC)
- Attributs du produit
- Tag location: N-terminal His Tag
- Pureté
- > 97 %
- Biological Activity Comment
- BMP7 (Bone morphogenetic protein 7), which belongs to the TGF-β superfamily, is a signaling molecule with the ability to promote bone formation. BMP7 has also been implicated in various types of cancer, including breast cancer. It has been reported that BMP7 treatment induced cell growth promotion of MDA-MB-231 breast cancer line. To test the effect of BMP7 on cell proliferation, MDA-MB-231 cells were seeded into triplicate wells of 96-well plates at a density of 2,000 cells/well and allowed to attach overnight, then the medium was replaced with serum-free standard DMEM prior to the addition of various concentrations of BMP7. After incubated for 72h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10μL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37°C.
- Top Product
- Discover our top product BMP7 Protéine
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- Indications d'application
- Isoelectric Point: 8.5
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01 % SKL, 5 % Trehalose and Proclin300.
- Agent conservateur
- Dithiothreitol (DTT), Other preservative, ProClin
- Précaution d'utilisation
- This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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- Antigène
- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
- Abstract
- BMP7 Produits
- Synonymes
- bmp-7 Protein, bmp7 Protein, op-1 Protein, BMP7 Protein, zgc:153025 Protein, OP-1 Protein, OP1 Protein, BMP-7 Protein, fb83f09 Protein, wu:fb83f09 Protein, bone morphogenetic protein 7 Protein, bone morphogenetic protein 7, gene 1 L homeolog Protein, bone morphogenetic protein 7b Protein, bone morphogenetic protein 7, gene 2 L homeolog Protein, bone morphogenetic protein 7a Protein, BMP7 Protein, bmp7.1.L Protein, LOC100136282 Protein, bmp7b Protein, Bmp7 Protein, LOC100008826 Protein, bmp7.2.L Protein, bmp7a Protein
- Sujet
- Alternative Names: OP1, Osteogenic Protein-1, Eptotermin alfa
- Poids moléculaire
- 16.9kDa
- UniProt
- P23359
- Pathways
- Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
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