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HUS1 Protein (AA 1-280) (His tag)

HUS1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667288
  • Antigène Voir toutes HUS1 Protéines
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-280
    Origine
    • 5
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette HUS1 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    HUS1, 1-280aa, Human, His tag, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HUS1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 40% Glycerol
    Stock
    4 °C
  • Antigène
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Autre désignation
    HUS1 (HUS1 Produits)
    Synonymes
    hHUS1 Protein, mHus1 Protein, XHus1 Protein, hus1 Protein, HUS1 checkpoint clamp component Protein, checkpoint clamp complex protein Hus1 Protein, HUS1 checkpoint clamp component L homeolog Protein, HUS1 Protein, Hus1 Protein, hus1 Protein, hus1.L Protein
    Sujet
    HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex. This protein associates with Rad9 and Rad1 to form the 9-1-1(RAD9-RAD1-HUS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis, cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a clamp-clamp loader pair during the DNA damage response. Recombinant human HUS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: checkpoint protein HUS1,. NCBI no.: NP_004498
    Poids moléculaire
    33.8 kDa (300aa), confirmed by MALDI-TOF
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