CHMP4A Protein (AA 1-265) (His tag)

N° du produit ABIN667654

Détail du produit

Antigène: CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))

Type de proteíne: Recombinant

Attributs du protein: AA 1-265

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CHMP4A protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CHMP4A, 1-265aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 200mM NaCl, 0.1mM PMSF, 1mM EDTA

Stock: 4 °C

Détail du antigène

Antigène: CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))

Autre désignation: CHMP4A (CHMP4A Produits)

Synonymes: C14orf123 Protein, CHMP4 Protein, CHMP4B Protein, HSPC134 Protein, SHAX2 Protein, SNF7 Protein, SNF7-1 Protein, VPS32-1 Protein, VPS32A Protein, charged multivesicular body protein 4A Protein, CHMP4A Protein

Sujet: CHMP4A (Chromatin-modifying protein 4a) belongs to the SNF7 family and functions as chromatin-modifying proteins. It probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. Also during HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins via the association of CHMP4 and a protein recruited by HIV-1 p6, which is present in viral Gag assembly and budding. CHMP4A expressed at higher level in heart, kidney, liver and skeletal muscle. Recombinant human CHMP4A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: chromatin modifying protein 4A, CHMP4, CHMP4B, HSPC134, SHAX2, SNF7, SNF7-1, VPS32-1, VPS32A. NCBI no.: NP_054888

Poids moléculaire: 32.0kDa (285aa), confirmed by MALDI-TOF