PARD6B Protein (His tag)
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- Antigène Voir toutes PARD6B Protéines
- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PARD6B protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PARD6B Protéine
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- Commentaires
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Synonyms: Partitioning defective 6 homolog beta, PAR6B
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol, 0.2 M NaCl
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
- Autre désignation
- PARD6B (PARD6B Produits)
- Synonymes
- PARD6B Protein, AV025615 Protein, Par6b Protein, PAR6B Protein, par-6 Protein, par6 Protein, pard6beta Protein, si:dkey-192i18.6 Protein, PAR-6 Protein, PAR-6B Protein, par-6 family cell polarity regulator beta Protein, par-6 family cell polarity regulator beta S homeolog Protein, par-6 partitioning defective 6 homolog beta (C. elegans) Protein, PARD6B Protein, Pard6b Protein, pard6b.S Protein, pard6b Protein
- Sujet
- Partitioning defective 6 homolog beta, also known as PARD6B, is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. Cellular asymmetry is critical for the development of multicellular organisms. PARD (partitioning-defective) proteins play important roles in asymmetric cell division and polarized growth, whereas Cdc42 and Rac mediate establishment of cell growth and polarity and contribute to oncogenic transformation by Ras. It is expressed in pancreas and in both adult and fetal kidney, and is weakly expressed in placenta and lung. Recombinant human PARD6B protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Poids moléculaire
- 43.6 kDa (395aa)
- NCBI Accession
- NP_115910
- Pathways
- Cell-Cell Junction Organization
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