TEF Protein (AA 1-303) (His tag)

N° du produit ABIN6387225

Détail du produit

Antigène: TEF (Thyrotrophic Embryonic Factor (TEF))

Type de proteíne: Recombinant

Attributs du protein: AA 1-303

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TEF protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMSDAGGG KKPPVDPQAG PGPGPGRAAG ERGLSGSFPL VLKKLMENPP REARLDKEKG KEKLEEDEAA AASTMAVSAS LMPPIWDKTI PYDGESFHLE YMDLDEFLLE NGIPASPTHL AHNLLLPVAE LEGKESASSS TASPPSSSTA IFQPSETVSS TESSLEKERE TPSPIDPNCV EVDVNFNPDP ADLVLSSVPG GELFNPRKHK FAEEDLKPQP MIKKAKKVFV PDEQKDEKYW TRRKKNNVAA KRSRDARRLK ENQITIRAAF LEKENTALRT EVAELRKEVG KCKTIVSKYE TKYGPL

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: TEF (Thyrotrophic Embryonic Factor (TEF))

Autre désignation: TEF (TEF Produits)

Synonymes: 2310028D20Rik Protein, tef Protein, tefb Protein, tefbeta Protein, wu:fa12f02 Protein, wu:fb11h02 Protein, zTEF[a] Protein, VBP Protein, xtef Protein, TEF Protein, DKFZp459A027 Protein, dbp Protein, TEF2 Protein, zgc:112180 Protein, TEF, PAR bZIP transcription factor Protein, thyrotroph embryonic factor Protein, thyrotrophic embryonic factor a Protein, thyrotrophic embryonic factor Protein, D site of albumin promoter (albumin D-box) binding protein L homeolog Protein, thyrotrophic embryonic factor b Protein, TEF Protein, Tef Protein, tefa Protein, tef Protein, dbp.L Protein, tefb Protein

Sujet: Thyrotroph embryonic factor isoform 1, also known as TEF, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSH beta promoter. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by down-regulating beta chain expression of cytokine receptors. Recombinant human TEF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 35.6kDa (326aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_003207

UniProt: Q10587