RPS19 Protein (AA 1-145) (His tag)

N° du produit ABIN6387234

Détail du produit

Antigène: RPS19 (Ribosomal Protein S19 (RPS19))

Type de proteíne: Recombinant

Attributs du protein: AA 1-145

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RPS19 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMPGVTVK DVNQQEFVRA LAAFLKKSGK LKVPEWVDTV KLAKHKELAP YDENWFYTRA ASTARHLYLR GGAGVGSMTK IYGGRQRNGV MPSHFSRGSK SVARRVLQAL EGLKMVEKDQ DGGRKLTPQG QRDLDRIAGQ VAAANKKH

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 40 % glycerol, 2  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: RPS19 (Ribosomal Protein S19 (RPS19))

Autre désignation: RPS19 (RPS19 Produits)

Synonymes: DBA Protein, DBA1 Protein, S19 Protein, Dsk3 Protein, 30S ribosomal protein S19 Protein, 40S ribosomal protein S19 Protein, ribosomal protein S19 Protein, rps19 Protein, rps-19 Protein, RPS19 Protein, Rps19 Protein

Sujet: RPS19 belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. Recombinant human RPS19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 18.4kDa (168aa), confirmed by MALDI-TOF

NCBI Accession: NP_001013

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly