MINA Protein (AA 1-465) (His tag)

N° du produit ABIN6387478

Détail du produit

Antigène: MINA (MYC Induced Nuclear Antigen (MINA))

Type de proteíne: Recombinant

Attributs du protein: AA 1-465

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MINA protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MPKKAKPTGS GKEEGPAPCK QMKLEAAGGP SALNFDSPSS LFESLISPIK TETFFKEFWE QKPLLIQRDD PALATYYGSL FKLTDLKSLC SRGMYYGRDV NVCRCVNGKK KVLNKDGKAH FLQLRKDFDQ KRATIQFHQP QRFKDELWRI QEKLECYFGS LVGSNVYITP AGSQGLPPHY DDVEVFILQL EGEKHWRLYH PTVPLAREYS VEAEERIGRP VHEFMLKPGD LLYFPRGTIH QADTPAGLAH STHVTISTYQ NNSWGDFLLD TISGLVFDTA KEDVELRTGI PRQLLLQVES TTVATRRLSG FLRTLADRLE GTKELLSSDM KKDFIMHRLP PYSAGDGAEL STPGGKLPRL DSVVRLQFKD HIVLTVLPDQ DQSDETQEKM VYIYHSLKNS RETHMMGNEE ETEFHGLRFP LSHLDALKQI WNSPAISVKD LKLTTDEEKE SLVLSLWTEC LIQVV

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MINA (MYC Induced Nuclear Antigen (MINA))

Autre désignation: MINA (MINA Produits)

Synonymes: MDIG Protein, MINA53 Protein, NO52 Protein, ROX Protein, 1810047J07Rik Protein, 2410057H13Rik Protein, 3830408E23Rik Protein, AI449204 Protein, Mina53 Protein, mina Protein, MGC83527 Protein, MINA Protein, DKFZp459K0725 Protein, Mina Protein, ribosomal oxygenase 2 Protein, MYC induced nuclear antigen Protein, ribosomal oxygenase 2 L homeolog Protein, RIOX2 Protein, Riox2 Protein, MINA Protein, riox2.L Protein, riox2 Protein

Sujet: MINA is an oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. This protein is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. It also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. MINA may play an important role in cell growth and survival. It may be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. Recombinant human MINA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 54.9kDa(485aa)