COPE Protein (AA 1-308) (His tag)

N° du produit ABIN5779054

Détail du produit

Antigène: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Type de proteíne: Recombinant

Attributs du protein: AA 1-308

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette COPE protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMAPPAPG PASGGSGEVD ELFDVKNAFY IGSYQQCINE AQRVKLSSPE RDVERDVFLY RAYLAQRKFG VVLDEIKPSS APELQAVRMF ADYLAHESRR DSIVAELDRE MSRSVDVTNT TFLLMAASIY LHDQNPDAAL RALHQGDSLE CTAMTVQILL KLDRLDLARK ELKRMQDLDE DATLTQLATA WVSLATGGEK LQDAYYIFQE MADKCSPTLL LLNGQAACHM AQGRWEAAEG LLQEALDKDS GYPETLVNLI VLSQHLGKPP EVTNRYLSQL KDAHRSHPFI KEYQAKENDF DRLVLQYAPS A

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid, In Phosphate buffered saline (  pH 7.4) containing 20 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Autre désignation: COPE (COPE Produits)

Synonymes: COPE Protein, DDBDRAFT_0189670 Protein, DDBDRAFT_0233799 Protein, DDB_0189670 Protein, DDB_0233799 Protein, DKFZp469K1716 Protein, MGC80063 Protein, MGC130714 Protein, epsilon-COP Protein, 1110005D17Rik Protein, Cope1 Protein, coatomer protein complex subunit epsilon Protein, coatomer protein complex epsilon subunit Protein, coatomer protein complex subunit epsilon S homeolog Protein, coatomer protein complex, subunit epsilon Protein, COPE Protein, copE Protein, cope.S Protein, cope Protein, Cope Protein

Sujet: COPE is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. Recombinant human COPE protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 36.9 kDa (331aa) confirmed by MALDI-TOF

NCBI Accession: NP_009194

UniProt: O14579