Galectin 2 Protein (AA 1-130) (His tag)

N° du produit ABIN6387705

Détail du produit

Antigène: Galectin 2 (LGALS2) (Lectin, Galactoside-Binding, Soluble, 2 (LGALS2))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 1-130

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Galectin 2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMSEKFEV KDLNMKPGMS LKIKGKIHND VDRFLINLGQ GKETLNLHFN PRFDESTIVC NTSEGGRWGQ EQRENHMCFS PGSEVKITIT FQDKDFKVTL PDGHQLTFPN RLGHNQLHYL SMGGLQISSF KLE

Pureté: > 95 % by SDS - PAGE

Biological Activity Comment: The ED50 for this effect is equal or higher than 20 ug/ml. Measured by its ability to agglutinate human red blood cells.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Bioactivity Validated

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.1M NaCl, 10 % glycerol,1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Galectin 2 (LGALS2) (Lectin, Galactoside-Binding, Soluble, 2 (LGALS2))

Autre désignation: Lgals2 (LGALS2 Produits)

Synonymes: LGALS3 Protein, galectin-2 Protein, HL14 Protein, 2200008F12Rik Protein, AI324147 Protein, LGALS2 Protein, hl14 Protein, Drgal1-L3 Protein, lgals1l3 Protein, zgc:66283 Protein, Drgal1-L2 Protein, lgals1l2 Protein, zgc:86752 Protein, galectin 2 Protein, lectin, galactose-binding, soluble 2 Protein, lectin, galactoside binding soluble 2 Protein, lectin, galactoside-binding, soluble, 2b Protein, lectin, galactoside-binding, soluble, 2a Protein, LGALS2 Protein, Lgals2 Protein, lgals2 Protein, lgals2b Protein, lgals2a Protein

Sujet: Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Lgals2 is a monomeric or homodimeric prototype galectin that is expressed in hepatoma, stomach epithelial cells and in colorectal and neural tumors. It induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-a (LTA) with possible implications in risk of myocardial infarction. Human and mouse Lgals2 share approximately 65 % amino acid sequence similarity. Recombinant Mouse Lgals2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 17.3 kDa (153aa), confirmed by MALDI-TOF

NCBI Accession: NP_079898

UniProt: Q9CQW5