IL-6 Protein (AA 30-212)
Aperçu rapide pour IL-6 Protein (AA 30-212) (ABIN7676726)
Antigène
Voir toutes IL-6 (IL6) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 30-212
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Séquence
- MVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
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Purification
- > 95% by SDS-PAGE
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niveau d'endotoxine
- < 1 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 1ng/ml.
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Interleukin 6 (IL6) (AA 30-212) protein (His tag,mFc Tag)
IL6 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, AM, ADA, ScA
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 28-212) (Active) protein (His tag)IL6 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 29-212) (Active) proteinIL6 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE analysis. Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Origine: Souris Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 30-212) (Active) protein (His tag)IL6 Origine: Humain Hôte: HEK-293 Cells > 97 % AcA, CC Active
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Origine: Rat Hôte: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
Interleukin 6 (IL6) (AA 30-212) (Active) protein (His tag)IL6 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, AcA Active
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Bioactivity Validated
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4)
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Conseil sur la manipulation
- Avoid repeated freezing and thawing cycles
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Autre désignation
- IL-6
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Sujet
- IL6, also known as interleukin 6. It is a cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. This protein plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. Recombinant human IL6 protein was expressed in E. coli and purified by using conventional chromatography techniques.
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Poids moléculaire
- 20.9 kDa (184aa)
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NCBI Accession
- NP_000591
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Pathways
- Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Antigène
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