SPOCK3 Protein (AA 22-436) (His tag)

N° du produit ABIN6387812

Détail du produit

Antigène: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Type de proteíne: Recombinant

Attributs du protein: AA 22-436

Origine: Souris

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette SPOCK3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: AAAAVAVAGG RSDGGNFLDE KQWLTTISQY DKEVGQWNKF RDEVEDDYFR TWNPGKPFDQ ALDPAKDPCL KTKCSRHKVC ITQDAQTALC ISHRRLTHSM KEVGGSHKQW RGLPSSTCKP CPIAYASPVC GSDGHSYSSQ CKLEYQACVL GKQISIKCEG RCPCPSDKSM NIGRNVKRAC SDLEFREVAN RLRDWFKALH ESGSQNKKTK ALLRPERSRF DTSILPICKD SLGWMFNRLD TNYDLLLDQS ELGSIYLDKN EQCTKAFFNS CDTYKDSLIS NNEWCYCFQR QQDPPCHTEL SNIQKRQGIK KLLGQYIPLC DEDGYYKPTQ CHGSVGQCWC VDRYGNEVVG SRINGVADCA IDFEISGDFA SGDFREWTDD EGEEDDIMND KDDIEDDDED EGDDDDDGDV HDGYILEHHH HHH

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Autre désignation: Spock3 (SPOCK3 Produits)

Synonymes: im:7139568 Protein, si:dkey-285b22.1 Protein, HSAJ1454 Protein, TES-3 Protein, TICN3 Protein, Testican-3 Protein, 2900045C01Rik Protein, AI428471 Protein, mKIAA4039 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 Protein, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3 Protein, spock3 Protein, SPOCK3 Protein, Spock3 Protein

Sujet: Spock3, also known as testican-3, is a nervous system-expressed heparan sulfate proteoglycan belonging to a subgroup of the BM-40/SPARC/osteonectin family, the role of which in brain development is unclear. It inhibits the processing of pro-matrix metalloproteinase 2(MMP-2) by MT1-MMP and MT3-MMP. It is mostly confined to the developmental stage of the brain. Recombinant mouse Spock3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 47.9kDa (423aa) 40-57kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_001239549

UniProt: Q8BKV0

Pathways: Glycosaminoglycan Metabolic Process