Interleukin 11 Receptor, alpha Chain 1 (IL11RA1) (AA 24-371) protein (His tag)

N° du produit ABIN6387873

Détail du produit

Antigène: Interleukin 11 Receptor, alpha Chain 1 (IL11RA1)

Type de proteíne: Recombinant

Attributs du protein: AA 24-371

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: His tag

Application: SDS-PAGE (SDS)

Séquence: LEASEEVELE PCLAPSLEQQ EQELTVALGQ PVRLCCGRAE RGGHWYKEGS RLAPAGRVRG WRGRLEIASF LPEDAGRYLC LARGSMIVLQ NLTLITGDSL TSSNDDEDPK SHRDPSNRHS YPQQAPYWTH PQRMEKKLHA VPAGNTVKFR CPAAGNPTPT IRWLKDGQAF HGENRIGGIR LRHQHWSLVM ESVVPSDRGT YTCLVENAVG SIRYNYLLDV LERSPHRPIL QAGLPANTTA VVGSDVELLC KVYSDAQPHI QWLKHIVING SSFGADGFPY VQVLKTADIN SSEVEVLYLR NVSAEDAGEY TCLAGNSIGL SYQSAWLTVL PEEDPTWTAA APEARYTDLE HHHHHH

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Interleukin 11 Receptor, alpha Chain 1 (IL11RA1)

Autre désignation: IL11ra1 (IL11RA1 Produits)

Synonymes: AI314697 Protein, GP130 Protein, Il-11ra Protein, Il11ra Protein, Il11ra2 Protein, NR1 Protein, interleukin 11 receptor, alpha chain 1 Protein, interleukin 11 receptor subunit alpha 1 Protein, Il11ra1 Protein

Sujet: FGFR4, as known as fibroblast growth factor receptor 4 isoform 1, is a glycosylated transmembrane receptor tyrosine kinase. This protein is widely expressed during embryonic development and in adult liver, kidney, and lung. Also, it is associates with beta-Klotho and sulfated glycosaminoglycans, and these interactions increase the affinity of FGFR4 for its ligands as well as its signaling capacity. This receptor signaling is additionally required for skeletal muscle development in limbs. Recombinant human FGFR4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 39.5kDa (356aa) 40-57kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_002002

UniProt: P22455

Pathways: Growth Factor Binding