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Uroplakin 3A Protein (UPK3A) (AA 19-207) (His tag)

UPK3A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN666629
  • Antigène Voir toutes Uroplakin 3A (UPK3A) Protéines
    Uroplakin 3A (UPK3A)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 19-207
    Origine
    • 3
    • 1
    • 1
    Humain
    Source
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Uroplakin 3A protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    UPK3A, 19-207aa, Human, His tag, E.coli
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product UPK3A Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl
    Stock
    4 °C
  • Antigène
    Uroplakin 3A (UPK3A)
    Autre désignation
    UPK3A (UPK3A Produits)
    Synonymes
    UP3A Protein, UPIII Protein, UPIIIA Protein, UPK3 Protein, upk3 Protein, upiii Protein, MGC75921 Protein, 1110017C07Rik Protein, UP3a Protein, Upk3 Protein, up3a Protein, upiiia Protein, upk3a Protein, xUPIII Protein, uroplakin 3A Protein, uroplakin 3 Protein, uroplakin 3A L homeolog Protein, UPK3A Protein, upk3a Protein, Upk3a Protein, LOC100008738 Protein, upk3a.L Protein
    Sujet
    UPK3A belongs to the uroplakin-3 family. Uroplakins (UP) are key components of the urothelium. They are transmembrane proteins that pass the lipid bilayer once (UPII, UPIIIa, and UPIIIb) or four times (UPIa and UPIb, both belonging to the 'tetraspanin' family). All have large luminal/extracellular domains, but only UPIIIa and UPIIIb have significant cytoplasmic portions in their C-termini. UPK3A is a highly specific and moderately sensitive immunohistochemical marker for primary and metastatic urothelial carcinomas. Mutations in this gene may be associated with renal adysplasia Recombinant human UPK3A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Uroplakin-3a, UPK3. NCBI no.: BAA31460
    Poids moléculaire
    23.1kDa (214aa), confirmed by MALDI-TOF
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