PTTG1 Protein (AA 1-202) (His tag)

N° du produit ABIN666649

Détail du produit

Antigène: PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-202

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PTTG1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PTTG1, 1-202 aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 80 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1 M NaCl, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))

Autre désignation: PTTG1 (PTTG1 Produits)

Synonymes: EAP1 Protein, HPTTG Protein, PTTG Protein, TUTR1 Protein, PTTG1 Protein, securin Protein, AW555095 Protein, C87862 Protein, Pttg Protein, Pttg3 Protein, Securin Protein, Protein Cut2 Protein, pituitary tumor-transforming 1 Protein, pituitary tumor-transforming gene 1 Protein, securin, sister chromatid separation inhibitor Protein, PTTG1 Protein, Pttg1 Protein, cut2 Protein

Sujet: PTTG1, also known as Securin, is primarily involved in the regulation of sister chromatid separation during cell division. It has two identified roles, the first one is to help the transport of separase(cysteine protease) to the nucleus and the second role is to inhibit the catalytic activity of separase. It is ubiquitinated by the Anaphase Promoting Complex (APC), and then degraded by the Proteasome, releasing separase. Recombinant PTTG1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EAP1, HPTTG, PTTG, TUTR1, SECURIN, Pituitary tumor-transforming protein 1 ESP1 ASSOCIATED PROTEIN 1, Esp1-associated protein, MGC126883, MGC138276, Pds1, PTTG1 protein, PTTG1, Pituitary tumor transforming 1, PTTG 1, EAP 1, Cut2, Pituitary tumor transforming protein 1, AW555095, Pituitary tumor-transforming 1, isoform CRA_a, Pituitary tumor-transforming 1, isoform CRA_b, hPTTG, Pituitary tumor-transforming gene 1, TUTR 1, Pttg3, Pituitary tumor-transforming gene 1 protein, C87862, TUMOR TRANSFORMING 1, Tumor transforming protein 1,. NCBI no.: NP_004210

Poids moléculaire: 24.1 kDa (222aa), confirmed by MALDI-TOF.