Ensa Protein (AA 1-121) (His tag)

N° du produit ABIN666932

Détail du produit

Antigène: Ensa (ENSA) (Endosulfine alpha (ENSA))

Type de proteíne: Recombinant

Attributs du protein: AA 1-121

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Ensa protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: ENSA, 1-121aa, Human, His tag, E.coli

Pureté: > 90 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by BCA)

Buffer: Liquid. In 20mM Tris buffer(pH 8.0) containing 10% glycerol, 1mM DTT.

Stock: 4 °C

Détail du antigène

Antigène: Ensa (ENSA) (Endosulfine alpha (ENSA))

Autre désignation: ENSA (ENSA Produits)

Synonymes: ARPP-19e Protein, 1700020C18Rik Protein, 2610007F17Rik Protein, AI451924 Protein, ensa Protein, si:dkeyp-24a7.3 Protein, ensaa Protein, endosulfine alpha Protein, endosulfine alpha a Protein, endosulfine alpha S homeolog Protein, ENSA Protein, Ensa Protein, ensa Protein, ensaa Protein, ensa.S Protein

Sujet: ENSA, also known as alpha endosulfine, belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein is expressed in a wide range of tissues including muscle, brain, and endocrine tissues. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. Recombinant ENSA protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ARPP-19e, Alpha endosulfine isoform 3 Alpha endosulfine, ARPP 19e, Endosulfine alpha. NCBI no.: NP_004427

Poids moléculaire: 15.5 kDa (141aa), confirmed by MALDI-TOF.