HNMT Protein (AA 1-292) (His tag)

N° du produit ABIN667093

Détail du produit

Antigène: HNMT (Histamine N-Methyltransferase (HNMT))

Type de proteíne: Recombinant

Attributs du protein: AA 1-292

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HNMT protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: HNMT, 1-292 aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl(pH8.0) buffer containing 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: HNMT (Histamine N-Methyltransferase (HNMT))

Autre désignation: HNMT (HNMT Produits)

Synonymes: HMT Protein, HNMT-S1 Protein, HNMT-S2 Protein, hmt Protein, hnmt Protein, hnmt-s1 Protein, hnmt-s2 Protein, zgc:100917 Protein, HNMT Protein, 1500031F01Rik Protein, AI788969 Protein, HMT A Protein, hnmt-a Protein, hnmt-b Protein, histamine N-methyltransferase Protein, histamine N-methyltransferase S homeolog Protein, histamine N-methyltransferase-like Protein, histamine N-methyltransferase L homeolog Protein, HNMT Protein, hnmt.S Protein, hnmt Protein, Hnmt Protein, LOC100228106 Protein, hnmt.L Protein

Sujet: Histamine N-methyltransferase (HNMT) is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT inactivates histamine by N-methylation. Histamine is involved in regulation and modulation of immune response through the stimulation of four distinct subtypes of receptors, H1, H2, H3, and H4, present on the target cells. Histamine is inactivated by the histamine-metabolizing enzyme histamine N-methyltransferase (HNMT) in bronchus, kidney, and the central nervous system. It plays an important role in degrading histamine and in regulating the airway response to histamine. Recombinant human HNMT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Histamine N-methyltransferase isoform 1 , HMT, HNMT-S1, HNMT-S2, Histamine N-methyltransferase isoform 1 EC 2.1.1.8, Histamine N methyltransferase, Hnmt, HNMT S1, HNMT S2. NCBI no.: NP_008826

Poids moléculaire: 37 kDa (328 aa), confirmed by MALDI-TOF.