SAE1 Protein (AA 1-346) (His tag)

N° du produit ABIN667139

Détail du produit

Antigène: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-346

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SAE1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: SAE1, 1-346aa, Human, His-T7 tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))

Autre désignation: SAE1 (SAE1 Produits)

Synonymes: AOS1 Protein, HSPC140 Protein, SUA1 Protein, UBLE1A Protein, 2400010M20Rik Protein, 2610044L12Rik Protein, AL033372 Protein, AW743391 Protein, D7Ertd177e Protein, Sua1 Protein, Uble1a Protein, Aos1p Protein, Sua1p Protein, aos Protein, sae2a Protein, uble1a Protein, wu:fa28b04 Protein, zgc:86633 Protein, SUMO1 activating enzyme subunit 1 Protein, SUMO1 activating enzyme subunit 1 L homeolog Protein, SAE1 Protein, Sae1 Protein, sae1.L Protein, sae1 Protein

Sujet: SAE1, also known as AOS1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteasome. SAE1, which is a dimeric enzyme, functions as a UBLI E1 ligase mediating the ATP-dependent activation of UBL1. This protein can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. Recombinant human SAE1 protein, fused to His-T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AOS1, HSPC140, SUA1, UBLE1A, SUMO1 activating enzyme subunit 1, Ubiquitin-like 1-activating enzyme E1A, AOS 1, HSPC 140, SUA 1, UBLE 1A, UBL E1A, SAE 1, Ubiquitin like protein SUMO 1 activating enzyme. NCBI no.: NP_005491

Poids moléculaire: 42.2 kDa (378aa) confirmed by MALDI-TOF