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ITPA Protein (AA 1-194) (His tag)

ITPA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667158
  • Antigène Voir toutes ITPA Protéines
    ITPA (Inosine Triphosphatase (ITPA))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-194
    Origine
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 7
    • 6
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette ITPA protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    ITPA, 1-194aa, Human, His tag, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product ITPA Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
    Stock
    4 °C
  • Antigène
    ITPA (Inosine Triphosphatase (ITPA))
    Autre désignation
    ITPA (ITPA Produits)
    Synonymes
    DDBDRAFT_0215619 Protein, DDBDRAFT_0238062 Protein, DDB_0215619 Protein, DDB_0238062 Protein, 2010016I08Rik Protein, AU020102 Protein, Itp Protein, C20orf37 Protein, HLC14-06-P Protein, dJ794I6.3 Protein, ITPase Protein, NTPase Protein, si:ch73-18j6.1 Protein, si:dkey-19f21.1 Protein, inosine triphosphatase Protein, inosine triphosphatase (nucleoside triphosphate pyrophosphatase) Protein, Inosine triphosphate pyrophosphatase Protein, inosine triphosphatase S homeolog Protein, itpa Protein, ITPA Protein, LOC733043 Protein, Itpa Protein, pco148511 Protein, itpa.S Protein
    Sujet
    ITPA, also known as Inosine triphosphate pyrophosphatase, is an enzyme that catalyzes the pyrophosphohydrolysis of both ITP (inosine triphosphate) and dITP (deoxyinosine triphosphate) to IMP (inosine monophosphate) and diphosphate. IMP can be used as a substrate for purine nucleotide pathways. IMP can be phosphorylated to ITP, and ITPA can regulate the concentration of ITP in the cell by converting ITP back to IMP. Defects in ITPA result in ITPA deficiency which is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts. Recombinant human ITPA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C20orf37, dJ794I6.3, HLC14-06-P, ITPase, My049, OK/SW-cl.9, Inosine triphosphate pyrophosphatase. NCBI no.: NP_258412
    Poids moléculaire
    23.7kDa (215aa) confirmed by MALDI-TOF
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