TSTA3 Protein (AA 1-321) (His tag)

N° du produit ABIN667170

Détail du produit

Antigène: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-321

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TSTA3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: TSTA3, 1-321aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Autre désignation: TSTA3 (TSTA3 Produits)

Synonymes: FX Protein, P35B Protein, SDR4E1 Protein, AI256181 Protein, Tstap35b Protein, p35b Protein, sdr4e1 Protein, TSTA3 Protein, zgc:101805 Protein, si:dkey-235d18none Protein, Fx Protein, tissue specific transplantation antigen P35B Protein, tissue specific transplantation antigen P35B L homeolog Protein, TSTA3 Protein, Tsta3 Protein, tsta3 Protein, tsta3.L Protein

Sujet: TSTA3 is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. Recombinant human TSTA3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FX, P35B, SDR4E1, GDP-L-fucose synthase. NCBI no.: NP_003304

Poids moléculaire: 38.0 kDa (341aa) confirmed by MALDI-TOF