CBFB Protein (AA 1-182) (His tag)

N° du produit ABIN7279124

Détail du produit

Antigène: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Type de proteíne: Recombinant

Attributs du protein: AA 1-182

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CBFB protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CBFB, 1-182aa, Human, His tag, E.coli

Pureté: > 85 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM MES (pH 6.0) containing 0.1 mM PMSF, 10% Glycerol

Stock: 4 °C

Détail du antigène

Antigène: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Autre désignation: CBFB (CBFB Produits)

Synonymes: PEBP2B Protein, Cbfb Protein, pebp2b Protein, Pebp2 Protein, CBFB Protein, unp1266 Protein, cbf-beta Protein, cbfbeta Protein, pea2-beta Protein, pebp2-beta Protein, AI893578 Protein, PEA2 Protein, PEBP2b Protein, Pebpb2 Protein, core-binding factor beta subunit Protein, core binding factor beta subunit Protein, core-binding factor, beta subunit Protein, core-binding factor, beta subunit S homeolog Protein, core binding factor beta Protein, CBFB Protein, Cbfb Protein, cbfb Protein, cbfb.S Protein

Sujet: CBFB, also known as PEBP2B, is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). This protein is a non-DNA binding regulatory subunit and it allosterically enhances DNA binding by alpha subunit. Recombinant human CBFB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: PEBP2B (polyomavirus enhancer binding protein b), PEA2, CBF-beta, Core-binding factor, beta subunit. NCBI no.: NP_001746

Poids moléculaire: 23.6 kDa(202aa), confirmed by MALDI-TOF

Pathways: Regulation of Lipid Metabolism by PPARalpha