Tropomyosin Protein (AA 1-284) (His tag)

N° du produit ABIN667191

Détail du produit

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-284

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Tropomyosin protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: TPM1, 1-284aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Autre désignation: TPM1 (TPM1 Produits)

Synonymes: alpha-fTM Protein, Tm7 Protein, tpm1 Protein, MGC84844 Protein, AA986836 Protein, AI854628 Protein, TM2 Protein, Tm3 Protein, Tmpa Protein, Tpm-1 Protein, alpha-TM Protein, Alpha-tm Protein, Tma2 Protein, Tmsa Protein, TPM1 Protein, fb37a09 Protein, tm Protein, wu:fb37a09 Protein, CH1 Protein, alpha-tm Protein, alpha-tropomyosin Protein, C15orf13 Protein, CMD1Y Protein, CMH3 Protein, HTM-alpha Protein, TMSA Protein, TPMA Protein, Tm1 Protein, zgc:171719 Protein, zgc:55951 Protein, zgc:77009 Protein, tropomyosin 1 (alpha) Protein, tropomyosin Protein, tropomyosin 1 Protein, tropomyosin 1, alpha Protein, alpha-tropomyosin Protein, tropomyosin 1 L homeolog Protein, TPM1 Protein, tm7 Protein, Tpm1 Protein, tpma Protein, tpm1.L Protein, Smp_044010.2 Protein, LOC732984 Protein, tpm1 Protein

Sujet: TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. TPM1 is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. Recombinant human TPM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TPM1, CMD1Y, HTM-alpha, TMSA, Tropomyosin-1, Alpha-tropomyosin, Tropomyosin alpha-1 chain. NCBI no.: NP_000357

Poids moléculaire: 35.0 kDa (304aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher))

Pathways: Regulation of Actin Filament Polymerization