MCEE Protein (AA 37-176) (His tag)

N° du produit ABIN667242

Détail du produit

Antigène: MCEE (Methylmalonyl CoA Epimerase (MCEE))

Type de proteíne: Recombinant

Attributs du protein: AA 37-176

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MCEE protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: MCEE, 37-176aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 1mM DTT, 0.1mM PMSF, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: MCEE (Methylmalonyl CoA Epimerase (MCEE))

Autre désignation: MCEE (MCEE Produits)

Synonymes: MGC89112 Protein, zgc:112343 Protein, MGC116480 Protein, GLOD2 Protein, 1110007A04Rik Protein, methylmalonyl-CoA epimerase Protein, methylmalonyl CoA epimerase Protein, methylmalonyl-CoA epimerase S homeolog Protein, MCEE Protein, mcee Protein, mcee.S Protein, Mcee Protein

Sujet: MCEE catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids, odd chain-length fatty acids, and other metabolites. This protein deficiency is an autosomal recessive inborn error of amino acid metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria may present in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma. Recombinant human MCEE protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Methylmalonyl CoA epimerase, DL methylmalonyl CoA racemase, EC 5.1.99.1, GLOD2, Glyoxalase domain containing 2. NCBI no.: NP_115990

Poids moléculaire: 17.3 kDa (161aa) confirmed by MALDI-TOF

Pathways: Monocarboxylic Acid Catabolic Process