PMM1 Protein (AA 1-262) (His tag)

N° du produit ABIN667263

Détail du produit

Antigène: PMM1 (Phosphomannomutase 1 (PMM1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-262

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PMM1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PMM1, 1-262aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF

Stock: 4 °C

Détail du antigène

Antigène: PMM1 (Phosphomannomutase 1 (PMM1))

Autre désignation: PMM1 (PMM1 Produits)

Synonymes: Sec53 Protein, C77612 Protein, phosphomannomutase 1 Protein, phosphomannomutase 1 L homeolog Protein, PMM1 Protein, pmm1 Protein, Pmm1 Protein, pmm1.L Protein

Sujet: PMM1 (Phosphomannomutase 1) is an enzyme that involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. This enzyme catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. In addition, it may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. Recombinant human PMM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: phosphomannomutase 1, Sec53, PMMH22. NCBI no.: NP_002667

Poids moléculaire: 31.9kDa (282aa) confirmed by MALDI-TOF