RDBP Protein (AA 1-380) (His tag)

N° du produit ABIN667394

Détail du produit

Antigène: RDBP (RD RNA Binding Protein (RDBP))

Type de proteíne: Recombinant

Attributs du protein: AA 1-380

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RDBP protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: RDBP, 1-380aa, Human, His tag, E.coli

Pureté: > 85 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: RDBP (RD RNA Binding Protein (RDBP))

Autre désignation: RDBP (RDBP Produits)

Synonymes: CG5994 Protein, Dmel\\CG5994 Protein, NELF Protein, NELF-E Protein, Nelf-e Protein, anon-66Da Protein, cg5994 Protein, dNelf-E Protein, D6S45 Protein, RD Protein, RDBP Protein, RDP Protein, Rd Protein, Rdbp Protein, D17H6S45 Protein, Negative elongation factor E Protein, negative elongation factor complex member E Protein, negative elongation factor complex member E, Rdbp Protein, Nelf-E Protein, NELFE Protein, Nelfe Protein

Sujet: RDBP, also known as NELF-E, is a putative RNA binding protein. This protein is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b and negative transcription elongation factors, DSIF and NELF. DSIF and NELF, act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. RDBP has a functional RNA-binding domain, whose mutations impair transcription repression without affecting known protein-protein interactions. Recombinant human RDBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: RD RNA binding protein, D6S45, NELF-E, RD, RDP. NCBI no.: NP_002895

Poids moléculaire: 45.4 kDa (400aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)