EEF1E1 Protein (AA 1-174) (His tag)

N° du produit ABIN667425

Détail du produit

Antigène: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-174

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette EEF1E1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: EEF1E1, 1-174aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Autre désignation: EEF1E1 (EEF1E1 Produits)

Synonymes: p18 Protein, AIMP3 Protein, P18 Protein, 1110003A02Rik Protein, eukaryotic translation elongation factor 1 epsilon 1 Protein, eukaryotic translation elongation factor 1 epsilon 1 L homeolog Protein, EEF1E1 Protein, eef1e1.L Protein, eef1e1 Protein, Eef1e1 Protein

Sujet: EEF1E1, also known as, eukaryotic translation elongation factor 1 epsilon-1, shares sequence similarity with the amino-terminal ends of the Beta and Gamma subunits of EF-1. By specifically interacting with MetRS, this protein binds to a macromolecular tRNA synthtase complex that catalyzes the ligation of specific amino acids to their cognate tRNAs. Upon DNA damage, it translocates to the nucleus where it interacts with ATM and ATR, resulting in p53 activation. Recombinant human EEIF1E1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Eukaryotic translation elongation factor 1 epsilon-1, AIMP3, P18. NCBI no.: NP_004271

Poids moléculaire: 21.9 kDa (194aa) confirmed by MALDI-TOF

Pathways: Positive Regulation of Response to DNA Damage Stimulus