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ATF3 Protein (AA 1-181)

ATF3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN667497
  • Antigène Voir toutes ATF3 Protéines
    ATF3 (Activating Transcription Factor 3 (ATF3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-181
    Origine
    • 6
    • 3
    • 1
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    ATF3, 1-181aa, Human, E.coli
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ATF3 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl, pH8.0, 2M Urea, 20%Glycerol
    Stock
    4 °C
  • Antigène
    ATF3 (Activating Transcription Factor 3 (ATF3))
    Autre désignation
    ATF3 (ATF3 Produits)
    Synonymes
    zgc:55526 Protein, ATF3 Protein, LRG-21 Protein, LRF-1 Protein, LRFI Protein, atf-3 Protein, activating transcription factor 3 Protein, activating transcription factor 3 L homeolog Protein, atf3 Protein, ATF3 Protein, Atf3 Protein, atf3.L Protein
    Sujet
    ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter. Synonyms: Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3. NCBI no.: NP_001665
    Poids moléculaire
    20.6kDa (181aa)
    Pathways
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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