TPM3 Protein (AA 1-248) (His tag)

N° du produit ABIN667651

Détail du produit

Antigène: TPM3 (Tropomyosin 3 (TPM3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-248

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TPM3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: TPM3, 1-248aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: TPM3 (Tropomyosin 3 (TPM3))

Autre désignation: TPM3 (TPM3 Produits)

Synonymes: CAPM1 Protein, CFTD Protein, NEM1 Protein, OK/SW-cl.5 Protein, TM-5 Protein, TM3 Protein, TM30 Protein, TM30nm Protein, TM5 Protein, TPMsk3 Protein, TRK Protein, hscp30 Protein, cb674 Protein, fa17b11 Protein, fb83b01 Protein, fk41e01 Protein, hm:zeh0298 Protein, wu:fa17b11 Protein, wu:fb83b01 Protein, wu:fk41e01 Protein, zeh0298 Protein, zgc:77592 Protein, TPM3 Protein, Tm5NM Protein, Tpm-5 Protein, Tpm5 Protein, Trop-5 Protein, gamma-TM Protein, hTM30nm Protein, hTMnm Protein, tm3 Protein, tpm3 Protein, tpm3.L Protein, tropomyosin 3 Protein, tropomyosin 3, gamma Protein, tropomyosin 3 S homeolog Protein, TPM3 Protein, tpm3 Protein, Tpm3 Protein, tpm3.S Protein

Sujet: Tropomyosin alpha-3 chain, also known as TPM3, is member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Recombinant human TPM3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Tropomyosin alpha-3 chain, hscp30, NEM1, OK/SW-cl.5, TM-5, TM3, TM30 TM30nm, TPMsk, TRK. NCBI no.: NP_705935

Poids moléculaire: 31.6 kDa (272aa), confirmed by MALDI-TOF